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DTSTAMP:20260928T214325Z
UID:55a43cbd-f0c9-47bc-aebc-a86ee1e98227
DTSTART:20261028T090000Z
DTEND:20261028T170000Z
DESCRIPTION:Fundamental knowledge in infection biology accumulates at an in
 credible pace\, revealing new molecular targets that play key roles in inf
 ection\, replication\, and pathogen metabolism as well as essential host f
 actors.  These represent new opportunities for the development of novel a
 nti-infective strategies. However\, translation of fundamental discoveries
  into therapeutic applications has traditionally been hindered by a scarci
 ty of approaches for thorough functional validation. Recent technological
  breakthroughs have made large-scale screening of small molecules against 
 relevant targets by X-ray crystallography more accessible\, helping accele
 rate the development of small molecule inhibitors through structure-based 
 drug design.  This approach can now be applied by researchers on a large 
 scale to investigate the function of molecular targets and establish proof
  of concept of their therapeutic potential. In this webinar\, we will pre
 sent new technologies developed at EMBL Grenoble enabling fully automated\
 , large-scale fragment and ligand screening and their application to the s
 tudy and validation of key targets with strong therapeutic potential in in
 fection biology.This event is part of the webinar series “Integrating st
 ructural biology and bioinformatics to study infection”. You can follow 
 the link for more information about the series and its webinars.
LOCATION:\, 
SUMMARY:Automated X-ray fragment and ligand screening for therapeutic innov
 ation in infection biology
URL;VALUE=URI:https://www.ebi.ac.uk/training/events/automated-x-ray-fragmen
 t-and-ligand-screening-therapeutic-discovery-infection-biology
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