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DTSTAMP:20260807T063211Z
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DTSTART:20190527T090000Z
DTEND:20190728T235959Z
DESCRIPTION:# Overview\n\n\n* **Duration**: 3 weeks\, 5 hours per week\n* F
 ree\n* Certificate of achievement available on satisfactory completion\n* 
 **Start Date**: The course is run ‘live’ for 3 weeks from the start da
 te above. Once this period is over there will be no live monitoring of the
  forums\, but you can still join and complete the course during the remain
 ing period.\n\n### Why join the course?\n\nDisease outbreaks are still a b
 ig problem in our modern world. Comparison between two or more bacterial g
 enomes can help improve understanding of the causes of pathogenicity and o
 utbreaks of disease caused by bacteria. On this course you will learn how 
 to use the free Artemis Comparison Tool (ACT). Developed at the Wellcome S
 anger Institute\, ACT will help you to visualise the comparison of genomes
  and analyse the results.\n\n### Who is the course for?\n\nThis course wou
 ld benefit those interested in learning how to use tools to investigate an
 d research bacterial genomes\, and acquire bioinformatics skills to evalua
 te the role of microbial genes in disease. Learners will gain experience i
 n comparative genomics\, using the Artemis Comparison Tool to probe\, visu
 alise and compare genomes\, and analyse the results.\n\nThis course will b
 e of interest to anyone interested in microbiology\, including undergradua
 tes\, post-graduates\, biomedical researchers\, microbiologists\, bioinfor
 maticians\, teachers\, and healthcare professionals.\n\nThe opportunity to
  gain experience in using the Artemis Comparison Tool\, a computational to
 ol designed for comparative genomics\, will also be of interest to all tho
 se who have studied our pre-requisite courses: those with an interest in g
 enomics and disease outbreaks\, teachers and their 16-18-year-old science 
 and computing students.\n\nIdeally\, you will have completed [Bacterial Ge
 nomes: From DNA to Protein Function Using Bioinformatics][1] and [Bacteria
 l Genomes: Accessing and Analysing Microbial Genome Data][2] before joinin
 g this course.\n\n  [1]: /our-events/bacterial-genomes-dna-protein-functio
 n-bioinformatics-online-sep19/\n  [2]: /our-events/bacterial-genomes-acces
 sing-analysing-microbial-genome-data-feb19/\n\n# Programme\n\n### What top
 ics will you cover?\n\nWeek 1\n\n* Introduction to comparative genomics\n*
  Introduction to ACT Week 2\n* Analyse available data\n* Generate your own
  comparison files\n* Make your own comparisons in ACT Week 3\n* Identify p
 seudogenes in Mycobacterium leprae using ACT\n* Peer review project: Compa
 rative genomics on two clinically relevant plasmids from Shigella\n\n### W
 hat will you achieve?\n\nBy the end of the course\, you'll be able to...\n
 \n* Explain the advantages of comparative genomics\n* Explore basic tools 
 of ACT\n* Interpret results from already generated comparison files\n* Pro
 duce new comparisons and analyse results\n* Develop hypothesis based on re
 sults observation\n\n### What software or tools do you need?\n\nThis cours
 e will give you an opportunity to learn about and use Artemis Comparison T
 ool (ACT)\, a free tool used to display pairwise comparisons between two D
 NA sequences. To run this software effectively\, you will require a comput
 er (Windows\, Mac or Linux) with 2GB RAM. The current version of ACT requi
 res version 11 of Java to run successfully. Java 11 can be downloaded from
  [this link][1]. Older versions of ACT require Java 8 to run successfully.
  Java 8 can be downloaded from [this link][2].\n\n  [1]: https://www.oracl
 e.com/technetwork/java/javase/downloads/jdk11-downloads-5066655.html\n  [2
 ]: https://www.java.com/en/download/\n\n# Educators\n\n## Lead Educators\n
 \n### Dr Anna Protasio\n\nI am a researcher in parasitology and life scien
 ces. I am passionate about bioinformatics and how we can use these tools t
 o answer questions in biology.\n\n### Dr Christine Boinett\n\nI am a resea
 rcher in bacterial genetics and my interest is in understanding the develo
 pment of resistance in bacterial pathogens using next generation sequencin
 g techniques.\n\n### Dr. Ulrike Böhme\n\nI am a researcher in parasitolog
 y at the Wellcome Sanger Institute where I work as biocurator for Plasmodi
 um genomes.\n\n### Dr. Pablo Tsukayama\n\nI am a professor of microbiology
  at Universidad Peruana Cayetano Heredia and a visiting research scholar a
 t the Wellcome Sanger Institute. I study how pathogen populations evolve a
 nd spread in Peru.\n\n### Martin Aslett\n\nI am the IT Manager for the Wel
 lcome Genome Campus Advanced Courses and Scientific Conferences team. My i
 nterests lie in bioinformatics and its application to microbial genomics.\
 n\n### Matthew Dorman\n\nI am a graduate student at the Wellcome Sanger In
 stitute\, where I research the virulence and the molecular genetics of bac
 terial pathogens as part of the Infection Genomics programme.\n\n## Progra
 mme Lead Educator\n\n### Professor Nicholas Thomson\n\nI am a Group Leader
  at the Wellcome Sanger Institute. I provide scientific oversight for this
  course. I am interested in bacterial evolution and the spread of infectio
 us disease.\n\n# What's Included\n\nWellcome Genome Campus Advanced Course
 s and Scientific Conferences are offering everyone who joins this course a
  free digital upgrade\, so that you can experience the full benefits of st
 udying online for free. This means that you get:\n\n* Unlimited access to 
 this course\n* Includes any articles\, videos\, peer reviews and quizzes\n
 * Tests to validate your learning\n* A PDF Certificate of Achievement to p
 rove your success when you’re eligible\n\n
SUMMARY:Bacterial Genomes: Comparative Genomics using Artemis Comparison To
 ol (ACT)
URL;VALUE=URI:https://coursesandconferences.wellcomegenomecampus.org/our-ev
 ents/bacterial-genomes-compara-genomics-online-may19/
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