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DESCRIPTION:**This School is co-organized by SIB/ELIXIR Switzerland and [de
 .NBI/ELIXIR Germany](https://www.denbi.de/)**\n## Overview\nBiodiversity i
 s fundamental to ecosystem functioning\, yet it is facing unprecedented pr
 essure. Advances in the generation\, analysis and integration of omics dat
 a by bioinformatics tools are transforming our ability to study biodiversi
 ty across scales through comprehensive\, high-throughput molecular profili
 ng of organisms and ecosystems. This summer school aims to equip life scie
 ntists with extended knowledge and practical skills to address these chall
 enges. \n\nIt will follow a hackathon / mini-project format\, with around 
 20 hours dedicated to hands-on training and collaborative problem-solving.
  Each participant will work within a single group throughout the week\, fo
 stering deep engagement\, collaborative problem-solving\, and the exchange
  of knowledge and expertise. Experienced trainers will guide four groups\,
  focusing on the following topics:\n\n* **Biodiversity across scales – f
 rom eDNA to ecosystems**\n* **Pangenomes: Capturing genetic diversity beyo
 nd a single reference**\n* **Computing genomic essential biodiversity vari
 ables**\n* **Evolutionary and functional insights from large-scale compara
 tive genomics** \n\nTo complement the project work\, the programme will in
 clude lectures and a social activity. Participants will stay together in a
  comfortable hotel\, creating an environment that encourages informal exch
 anges and networking beyond the formal sessions. Accommodation and meals a
 re included in the registration fee\, allowing participants to focus entir
 ely on training\, collaboration\, and community building. \n\n\n##### Topi
 c 1: Biodiversity across scales – from eDNA to ecosystems\nThis project 
 introduces the background and conceptual foundations of environmental DNA 
 (eDNA) metabarcoding as a powerful tool for biodiversity assessment. Parti
 cipants will gain a theoretical overview of key laboratory steps\, from sa
 mple processing to sequencing\, and explore different bioinformatic pipeli
 nes that transform raw sequencing reads into taxonomic lists and ecologica
 l diversity metrics. Emphasis is placed on understanding methodological ch
 oices\, sources of bias\, and best practices across workflows. The project
  is designed as a hands-on training\, guiding participants step by step fr
 om raw sequencing data to interpretable biodiversity results. Each partici
 pant will build and run their own analysis pipeline\, enabling a practical
  understanding of metabarcoding data generation and analysis. The course c
 oncludes by highlighting ecological and applied use cases of metabarcoding
  in biodiversity research and monitoring.\n**Trainers**\nDr Vera Zizka\, T
 he State Museum of Natural History\, Karlsruhe\nDr Ameli Kirse\, Leibniz I
 nstitute for the Analysis of Biodiversity Change\n\n**Skills/experience ne
 eded for this topic**\n-basic command line experience\n-basic R software e
 xperience\n-basic knowledge in molecular sequencing data\n\n\n##### Topic 
 2: Capturing genetic diversity beyond a single reference\nIn this project\
 , participants will experience the fundamental workflow of genomic analysi
 s\, beginning with the quality assessment and de novo assembly of raw sequ
 encing reads. Participants will proceed to characterize the obtained genom
 e assemblies through structural and functional gene annotation\, followed 
 by variant calling to identify specific genetic differences. The project c
 oncludes with the construction of a graph-pangenome to model the full scop
 e of genetic diversity within a population.\n**Trainers**\nDr Marie Bolger
 \, Forschungszentrum Jülich\nDr Sebastian Beier\, Forschungszentrum Jüli
 ch\,\n\n**Skills/experience needed for this topic**\n-basic command line e
 xperience\n-some experience with sequencing technologies and associated da
 ta formats (eg.\, fasta\, fastq\, vcf)\n\n##### Topic 3: Computing genomic
  essential biodiversity variables\nEssential Biodiversity Variables (EBVs)
  are a set of standardized biological measurements designed to quantify an
 d report changes in biodiversity across time\, space\, and biological leve
 ls\, with the goal of informing and influencing policy‑making decisions.
  In this project\, participants will work in small groups to design and ca
 rry out a biodiversity genomics analysis aimed at quantifying EBVs. Starti
 ng from a conservation or management question\, they will use publicly ava
 ilable genomic datasets and develop an analysis plan\, spanning raw data q
 uality control\, read mapping\, and variant calling\, through to populatio
 n structure\, diversity\, inbreeding\, and effective population size metri
 cs. \nThe project emphasizes reproducible pipeline design using establishe
 d tools\, standard reference resources\, and careful interpretation of EBV
  outputs in the context of conservation\, bioeconomy\, and policy-making.\
 n**Trainers**\nDr Tristan Cumer\, Department of Ecology and Evolution\, Un
 iversity of Lausanne\, Switzerland\nDr Chiara Bortoluzzi anb Dr Christian 
 de Guttry\, Environmental Bioinformatics\, SIB Swiss Institute of Bioinfor
 matics\n\n**Skills/experience needed for this topic**\n-basic command line
  experience\n-basic R software experience\n**Nice to have:**\n-prior exper
 ience with sequencing technologies and associated data formats (e.g.\, FAS
 TA\, FASTQ\, VCF) would be beneficial\n-basic understanding of population 
 genetics may be helpful\n\n##### Topic 4: Evolutionary and functional insi
 ghts from large-scale comparative genomics \nIn this project\, participant
 s will work in small groups to design and carry out a comparative genomics
  study addressing an evolutionary or functional question. Starting from a 
 biological question\, they will identify relevant datasets\, plan appropri
 ate analyses (e.g. genome quality control\, orthology inference\, gene fam
 ily evolution\, functional annotation)\, and implement them using existing
  tools and resources. The project emphasizes methodological choices\, data
  interpretation\, and critical evaluation of results. Results will be synt
 hesized and presented at the end of the week.\n**Trainers**\nDr Natasha Gl
 over\, Comparative Genomics Group\, University of Lausanne and SIB Swiss I
 nstitute of Bioinformatics\nDr Robert Waterhouse\, Environmental Bioinform
 atics group\, SIB Swiss Institute of Bioinformatics\n\n**Skills/experience
  needed for this topic**\n-basic command line experience\n-basic familiari
 ty with at least one scripting language (Python or R)\n-general understand
 ing of genomics concepts (genes\, genomes\, annotations)\n *Nice to have:*
 \n-prior exposure to comparative genomics concepts (orthology\, gene famil
 ies\, synteny)\n-experience working with omics data (genomics\, transcript
 omics)\n-familiarity with bioinformatics workflows or pipelines\n-basic da
 ta visualization skills (R\, Python\, or similar)\n\n\n## Audience\nThis c
 ourse is designed for PhD students\, postdoctoral and other researchers in
  the life sciences from both academia and industry who are interested in b
 iodiversity bioinformatics.\n\n## Learning outcomes\nAt the end of the cou
 rse\, the participants are expected to:\n* understand the major challenges
  of biodiversity bioinformatics\n* have gained an in-depth knowledge of th
 e topic in which they participated\n* have played an active role in a grou
 p project and delivered a presentation of the results.\n\n## Prerequisites
 \n##### Knowledge / competencies\nThis course is designed for beginner to 
 intermediate users\, and requires the following general skills/experience:
 \n\n* Previous experience with sequencing technologies and associated data
  formats (eg.\, fasta\, fastq\, vcf)\n* Basic command-line usage (Linux/Un
 ix) \n* Basic familiarity with at least one scripting language (Python or 
 **R**)  \n\nMore specific prerequisites are listed in the topics paragraph
 s above. \n\n\n##### Technical\nParticipants are required to bring their o
 wn laptop with administrative rights\, allowing them to install software a
 nd/or packages during the course if needed. However\, we expect all requir
 ed software—details of which will be communicated later—to be installe
 d **prior to the course**.\n\n## Schedule - CET time zone\n\nNote that the
  details of the schedule are informative\, changes are possible.\n\n**Sund
 ay**\n~18h00 Arrival and registration \n19h00  Dinner\n20h15  Welcome sess
 ion\n\n**Monday**\n09h00  General introduction + introduction to the 4 top
 ics\n10h30  Break\n11h00  Introduction to the 4 topics and/or Project work
  in groups\n12h30  Lunch\n14h00  Project work in groups (including a break
 )\n17h15  Recap of the day\n17h30  End\n\n**Tuesday**\n09h00  Project work
  in groups\n10h30  Break\n11h00  Lecture\n11h45  Project work in groups\n1
 2h30  Lunch\n14h00  Project work in groups (including a break)\n17h15  Rec
 ap of the day\n17h30  End\n\n**Wednesday**\n09h00  Project work in groups\
 n10h30  Break\n11h00  Lecture\n11h45  Project work in groups\n12h30  Lunch
 \n14h00  Social Activity\n17h15  Recap of the day\n17h30  End\n\n**Thursda
 y**\n09h00  Project work in groups\n10h30  Break\n11h00  Lecture\n11h45  P
 roject work in groups\n12h30  Lunch\n14h00  Project work in groups + proje
 ct presentation preparation (including a break)\n17h15  Recap of the day\n
 17h30  End\n\n**Friday**\n09h00  Project presentations\n10h30  Break\n11h0
 0  Project presentations\n11h45  Conclusion\n12h00  Lunch &amp\; back home
 \n\n\n## Application\n\nThe registration fees for academics are **900 CHF 
 (~950 EUR)** and **1900 CHF (~2000 EUR)** for for-profit companies. Course
  fees and hotel accommodation (in single rooms)\, as well as meals are inc
 luded.\n\nApplicants will be contacted by email after submitting their app
 lication and invited to provide a **motivation letter** and complete a sho
 rt **survey** to let us know about your **topic preference(s)**. In the ev
 ent of oversubscription\, participants will be selected based on several c
 riteria\, which may extend the time required to confirm registration.\n\nY
 ou will be informed by email of your registration confirmation. Upon recep
 tion of the confirmation email\, participants will be asked to confirm att
 endance by paying the fees within 10 days.\n\nApplications will close on *
 *31 March 2026**. Deadline for free-of-charge cancellation is set to **2 A
 pril 2026**. Any cancellation after this date may be subject to penalties\
 , depending on the possibility of replacement by someone in the waiting li
 st.\n\n**Summary of the process:**\n- application using the button at the 
 top of the page\n- you receive an email containing instructions to send ba
 ck a motivation letter and to complete a survey to let us know your prefer
 ence(s)\n- validation of your participation or placed on a waiting list\n-
  payment\n\n\n## Venue and Time\nThe course will take place at the [Dorint
  Parkhotel Siegen](https://hotel-siegen.dorint.com/en/) in Germany.\n\nTo 
 ensure every participant easy traveling\, the school will start on Sunday 
 around 19h and end on Friday after lunch.\n\nPrecise information will be p
 rovided to the registered participants in due time.\n\n\n## Additional inf
 ormation\nCoordination: Helena Schnitzer (de.NBI and ELIXIR Germany) and G
 régoire Rossier (SIB).\n\n\nAt the end of the course\, we will provide a 
 *Certificate of Achievement* recommending 2 ECTS credits.\n\n\nYou are wel
 come to register to the SIB courses mailing list to be informed of all fut
 ure courses and workshops\, as well as all important deadlines using the f
 orm [here](https://lists.sib.swiss/mailman/listinfo/courses).\n\n\nPlease 
 note that participation in SIB courses is subject to our [general conditio
 ns](http://www.sib.swiss/training/terms-and-conditions).\n\n\nSIB abides b
 y the [ELIXIR Code of Conduct](https://elixir-europe.org/events/code-of-co
 nduct). Participants of SIB courses are also required to abide by the same
  code.\n\n\nFor more information\, please contact [us](mailto:gregoire.ros
 sier@sib.swiss\,h.schnitzer@fz-juelich.de).
SUMMARY:Biodiversity Bioinformatics Summer School
URL;VALUE=URI:https://www.sib.swiss/training/course/20260621_SSBIB
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