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VERSION:2.0
PRODID:icalendar-ruby
CALSCALE:GREGORIAN
BEGIN:VEVENT
DTSTAMP:20260710T032402Z
UID:aa4a846d-d4cf-4576-9fa1-16bf7673e002
DTSTART:20241204T090000Z
DTEND:20241204T170000Z
DESCRIPTION:Polygenic scores (PGS) are a measurement which represents genet
 ic predisposition for a heritable trait or phenotype by aggregating the ef
 fects of hundreds-to-millions of genetic variants into a single number. [T
 he PGS Catalog](https://pgscatalog.org) is the world’s largest FAIR (fin
 able\, accessible\, interoperable\, and reusable) repository of PGS along 
 with the relevant metadata required to evaluate and reuse them. PGS have e
 merged as a commonly used genomic tool that have [multiple research appli
 cations and potential clinical applications](https://genomemedicine.biomed
 central.com/articles/10.1186/s13073-024-01304-9). \n\nThis webinar will d
 emonstrate how to use scoring files from the PGS Catalog (or custom files)
  to calculate PGS in your own samples using the PGS Catalog Calculator ([p
 gsc\\_calc](https://github.com/PGScatalog/pgsc_calc/)). The pgsc\\_calc so
 ftware reproducibly automates PGS calculation in commonly used genotyping 
 formats (plink\, VCF) alongside capabilities for adjusting PGS in the con
 text of genetic ancestry (necessary for proper interpretation of PGS acros
 s diverse populations). This webinar introduces the software and describe
 s the ancestry adjustment process included in the Calculator\, along with 
 information about how to run the tool and interpret results.
LOCATION:\, 
SUMMARY:Calculating polygenic scores with the Polygenic Score Catalog Calcu
 lator
URL;VALUE=URI:https://www.ebi.ac.uk/training/events/calculating-polygenic-s
 cores-polygenic-score-catalog-calculator
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