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DTSTAMP:20260407T174705Z
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DTSTART:20261026T090000Z
DTEND:20261028T170000Z
DESCRIPTION:## Overview\nThis workshop aims to present the basics of Comput
 er-Aided Drug Design (CADD)\, taking examples from different therapeutic a
 reas and introducing appropriate mostly freely accessible tools. Participa
 nts will learn to perform and analyze real-world cases of tridimensional b
 iomolecular visualization\, ligand-protein docking\, ligand-protein co-fol
 ding\, ligand-based virtual screening\, protein target prediction\, small-
 molecule property calculations and bioisosteric design. \n\nThroughout the
  course\, we will use powerful\, yet simple and intuitive professional too
 ls\, commonly employed in molecular modelling\, drug design\, and bio- and
  chemo-informatics. In-house original CADD technologies and resources deve
 loped at SIB\, combined with third-party software will be employed. The le
 ctures and practices will be conducted by the scientific developers of the
  SIB resources\, who will be available to discuss individual research need
 s of the participants.\n\n## Audience\nThis course is designed for PhD stu
 dents\, postdoctoral and other researchers in the life sciences from both 
 academia and industry who are interested in drug design. \n\n## Learning o
 utcomes\nAt the end of the course\, the participants are expected to:\n\n*
  display biomacromolecules in 3D\, analyze ligand-protein complexes and pr
 oduce high-quality images and interactive sessions with UCSF ChimeraX\n* p
 erform molecular docking with the [SwissDock](https://www.swissdock.ch/) w
 ebtool and analyze interactions at the atomic level in ChimeraX\n* perform
  ligand-based screening on-line using [SwissSimilarity](http://www.swisssi
 milarity.ch/)\n* estimate the most probable protein targets of bioactive s
 mall molecules with [SwissTargetPrediction](http://www.swisstargetpredicti
 on.ch/)\n* compute ADME\, physicochemical\, pharmacokinetic\, druglikeness
  and related properties of molecules with [SwissADME](https://www.swissadm
 e.ch/) \n* perform bioisosteric design for an educated selection of molecu
 lar replacements in the context of lead optimization or scaffold hopping u
 sing [SwissBioisostere](http://www.swissbioisostere.ch/)\n*	predict struct
 ures of biomolecular complexes using co-folding tools such as AlphaFold an
 d Boltz\n\n\n## Prerequisites\n##### Knowledge / competencies\n*	Basic kno
 wledge in biology\n*	Basic knowledge in chemistry.\n\n\n\n##### Technical\
 nA Wi-Fi enabled laptop with two programs installed: UCSF ChimeraX and a w
 eb browser (recent version of Firefox or Chrome). Please click [HERE](http
 s://www.cgl.ucsf.edu/chimerax/download.html) to install the latest product
 ion release of UCSF ChimeraX. \nThere will be access to the eduroam and gu
 est WiFi network. \n\n## Schedule - CET time zone\n\n**Tentative program**
 \n\n**Day 1** 9:15 - 17:15\n\n**Day 2** 9:15 - 17:15\n\n**Day 3** 9:15 - 1
 7:15\n\n## Application\n\nThe registration fees for academics are **300 CH
 F** and **1500 CHF** for for-profit companies.\n\nYou will be informed by 
 email of your registration confirmation. Upon reception of the confirmatio
 n email\, participants will be asked to confirm attendance by paying the f
 ees within 5 days.\n\nApplications close on *28/09/2026*. Deadline for fre
 e-of-charge cancellation is set to *28/09/2026*. Cancellation after this d
 ate will not be reimbursed. Please note that participation in SIB courses 
 is subject to our [general conditions](https://www.sib.swiss/training/term
 s-and-conditions).\n\n## Venue and Time\nThis course will take place at th
 e University of Bern.\n\n\nThe course will start at 9:15 CET and end aroun
 d 17:15 CET.\n\n\nPrecise information will be provided to the registered p
 articipants in due time.\n\n\n## Additional information\nCoordination: Val
 eria Di Cola\, SIB Training Group.\n\nWe will recommend 0.75 ECTS credits 
 for this course (given a passed exam at the end of the course).\n\n\nYou a
 re welcome to register to the SIB courses mailing list to be informed of a
 ll future courses and workshops\, as well as all important deadlines using
  the form [here](https://lists.sib.swiss/mailman/listinfo/courses).\n\n\nP
 lease note that participation in SIB courses is subject to our [general co
 nditions](http://www.sib.swiss/training/terms-and-conditions).\n\n\nSIB ab
 ides by the [ELIXIR Code of Conduct](https://elixir-europe.org/events/code
 -of-conduct). Participants of SIB courses are also required to abide by th
 e same code.\n\n\nFor more information\, please contact [training@sib.swis
 s](mailto://training@sib.swiss).
SUMMARY:Computer-Aided Drug Design
URL;VALUE=URI:https://www.sib.swiss/training/course/20261026_CADDS
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