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DTSTAMP:20260708T103446Z
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DTSTART:20230703T120000Z
DTEND:20230704T140000Z
DESCRIPTION:The ELIXIR IDP Community F2F/hybrid meeting takes place from 13
 :00 CET to  14:00 CET  on Monday and Tuesday\, July 3rd and 4th 2023. Th
 is meeting is planned as a hybrid meeting\, with the F2F component at the 
 Clarion Congress Hotel Bratislava (Žabotova 2\, 811 04) in Bratislava\, S
 lovakia.\n\nThe meeting will be held immediately before the COST Action ML
 4NG Main Conference (4-7 July).\n\nCONTEXT\n	The ELIXIR IDP Community for 
 Intrinsically Disordered Proteins (IDPs) aims to develop standards\, tools
  and resources to accelerate the identification\, analysis and functional 
 characterisation of IDPs\, i.e. proteins containing regions that lack a st
 able secondary or tertiary structure and that are thought to be involved i
 n many human diseases\, including cancer\, Alzheimer’s and Parkinson’s
  disease.\n\nRecent developments in structure prediction\, exemplified by 
 the AlphaFold algorithm\, have opened up new challenges in protein modelli
 ng. Key challenges lie ahead in capturing protein dynamics and understandi
 ng how the context of a protein (mutations\, modifications\, environmental
  conditions\, etc.) influences its conformational behaviour. A crucial fac
 tor in achieving this is the way we describe and capture conformational en
 sembles. This presents a serious challenge\, as such representations have 
 to cover a wide range of protein behaviour\, from local switches between a
  few well-defined alternative conformations to intrinsically disordered pr
 oteins (IDPs) that sample an immense number of conformations in a random w
 alk-like manner.\n\nWhile the prediction of conformational switches has re
 cently made significant progress\, as illustrated in the last Critical Ass
 essment of protein Structure Prediction (CASP)\, the second challenge of m
 odelling IDPs remains largely unresolved due to the conformational and exp
 erimental uncertainty surrounding such dynamic molecular systems.\n\nThe E
 LIXIR IDP Community annual meeting of 2023 aims to unite experimentalists 
 and method developers to discuss these challenges and define joint opportu
 nities. The first part of the meeting will focus on evaluating conformatio
 nal ensembles against experimental data\, while the second will delve into
  representing the variability of conformational ensembles.\n\nBy bringing 
 together these two communities\, we hope to identify the opportunities and
  limitations of critically assessing IDP ensembles\, thus making progress 
 towards resolving the outstanding challenges in this field.\n\nWe will als
 o spend some time looking at the ELIXIR 2024-2028 Scientific Programme and
  explore possibilities how the IDP Community can contribute and benefit. 
 \n\nThis meeting has a limit of in-person attendees of 35 participants\, w
 ith no-limit on virtual participant numbers. A number of selected invited 
 participants will receive funding to attend the meeting. These will be spe
 cifically informed regarding the reimbursement arrangements. \n\nAgenda\n
 \nA first agenda draft can be found here and will bre updated iteratively
  before the meeting. \n\nAdditional Registration information\n\nPlease no
 te\, if you have selected to attend face to face\, this option is limited 
 to first come first served basis. All registrants will be informed via ema
 il regarding their registration. Please do not book any travel till after 
 you have been notified. \n\nTravel and venue\n\nOnce notified of your F2F
  attendance you will be expected to make your own travel and accommodation
  arrangements to the venue\, reimbursement information will be shared with
  invited attendees after their successful registration.\n\nRecommended acc
 ommodation (please consider shared reimbursement rules):\n\nClarion Congre
 ss Hotel Bratislava (Žabotova 2\, 811 04) in Bratislava\, Slovakia. \n\n
 Registration deadline:\n	    In presence participation: 11 June 2023\n
 	    Remote participation: 03 July 2023\n\nContacts:\n	katharina.heil@e
 lixir-europe.org &amp\; damiano.piovesan@unipd.it
SUMMARY:ELIXIR IDP Community F2F/hybrid meeting
URL;VALUE=URI:https://www.elixir-europe.org/events/elixir-idp-community-f2f
 hybrid-meeting-0
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