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DESCRIPTION:## Overview \n\nMachine Learning has become an essential tool i
 n Life Science\, letting scientists explore and learn from large and compl
 ex biological datasets. To collectively unravel the puzzle of life\, we mu
 st ensure that machine learning models make the most of the available data
  and that they are correctly generalizable\, robust\, and interpretable to
  provide trustworthy and actionable insights. This advanced course is desi
 gned for scientists who already have a foundational understanding of machi
 ne learning and seek to enhance their core skills in this domain.   \n\nTh
 is course focuses on best practices and advanced techniques in Machine Lea
 rning\, aiming to provide you with the tools needed to develop more accura
 te\, generalizable\, and transparent models.   \n\n\n## Audience  \n\nThis
  course is addressed to life scientists\, bioinformaticians\, and computat
 ional biologists who would like to learn more about general best practices
  in Machine Learning and get more out of their Machine Learning models: mo
 re precise hyper-parameters\, more generalizable models\, and more interpr
 etable models. \n\n\n## Learning outcomes  \n\nAt the end of this course\,
  you will be able to:\n\n* Use the hyperopt library to efficiently explore
  your hyper-parameter space with Bayesian Optimization and tune your model
 s.  \n* Evaluate the generalizability of your generated models using best 
 practices such as nested cross-validation.   \n* Explain the role of each 
 feature in your model's prediction\, even for so-called "black-box" models
   \n* Examine the results of your models and assess their quality. \n\n## 
 Prerequisites  \n\n##### Knowledge / competencies  \n\n* Good knowledge of
  the basics of machine learning\, such as K-fold cross-validation\, Decisi
 on Tree\, and evaluation metrics.  \n\n* Fluency with the Python programmi
 ng language\, including working knowledge of standard data analysis librar
 ies such as numpy\, pandas\, matplotlib\, and scikit-learn.  \n\n* Familia
 rity with different omics data technologies (highly recommended).  \n\nThe
  competencies and knowledge levels required correspond to those taught in 
 courses such as [Introduction to Machine Learning in Life Sciences](https:
 //github.com/sib-swiss/intro-machine-learning-training). \n\nBefore applyi
 ng to this course\, please self-assess your Python and Machine Learning sk
 ills using the [**quiz**](https://forms.office.com/e/aWAGV8tbix) here.   W
 e recommend a score of at least 6/10.    \n\n##### Technical  \n\nYour lap
 top must have a recent Python version (minimum 3.0) and several Python lib
 raries installed. The needed libraries will be indicated in the course [Gi
 tHub repo](https://github.com/sib-swiss/intermediate-machine-learning-trai
 ning/) and here in due time.  \n\n## Schedule - CET time zone  \n\n| Sched
 ule CEST | | \n| ---  | ----------- |\n|  09:00-12:00 | Theory\, demonstra
 tion and micro-exercises | \n |  12:00-13:00  | Lunch break | \n |  13:00-
 16:00  | Group work | \n |  16:00-17:00 | Group work debrief and conclusio
 ns | \n\nPlease take note of the following information: \n\nThis schedule 
 is subject to change to allow time for questions and discussions with the 
 course participants. \n\nThe group work involves a project designed by the
  course trainers\, where participants collaborate in smaller groups to add
 ress the same question. \n\nIn addition to the suggested projects\, the gr
 oup work may also incorporate some Bring Your Own Data components. However
 \, this depends on the data's cleanliness\, the feasibility of your object
 ive\, and the interest of other participants. In any case\, the instructor
 s will be happy to discuss your data. \n\n## Application \n\nThe registrat
 ion fees for academics are 100 CHF and 500 CHF for for-profit companies. \
 n\nYou will be informed by email of your registration confirmation. Upon r
 eception of the confirmation email\, participants will be asked to confirm
  attendance by paying the fees within 5 days. \n\nWhile participants are r
 egistered on a first come\, first served basis\, exceptions may be made to
  ensure diversity and equity\, which may increase the time before your reg
 istration is confirmed. \n\nApplications close on **03.11.2026** or as soo
 n as the maximum capacity has been reached. The deadline for free-of-charg
 e cancellation is set to **03.11.2026** . Cancellation after this date wil
 l not be reimbursed. Please note that participation in SIB courses is subj
 ect to our [general conditions](https://www.sib.swiss/training/terms-and-c
 onditions). \n\n## Venue and Time \n\nThis course will be streamed.  \n\nT
 he course will start at 9:00 and end around 17:00. Precise information wil
 l be provided to the participants in due time. \n\nPrecise information wil
 l be provided to the participants in due time. \n\n## Additional informati
 on \n\nCoordination: Grégoire Rossier\, SIB Training Group.\n\nAt the end
  of the course\, we will provide a *Certificate of Attendance* or a *Certi
 ficate of Achievement* recommending 0.25 ECTS credits (given a passed exam
 ). \n\nYou are welcome to register to the SIB courses mailing list to be i
 nformed of all future courses and workshops\, as well as all important dea
 dlines using the form [here](https://lists.sib.swiss/postorius/lists/cours
 es.lists.sib.swiss/). \n\nPlease note that participation in SIB courses is
  subject to our [general conditions](https://www.sib.swiss/training/terms-
 and-conditions). \n\nSIB abides by the [ELIXIR Code of Conduct](https://el
 ixir-europe.org/events/code-of-conduct). Participants of SIB courses are a
 lso required to abide by the same code. \n\nFor more information\, please 
 contact [training@sib.swiss](mailto://training@sib.swiss).
SUMMARY:Ensuring More Accurate\, Generalisable\, and Interpretable Machine 
 Learning Models for Bioinformatics
URL;VALUE=URI:https://www.sib.swiss/training/course/20261117__INTML
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