BEGIN:VCALENDAR
VERSION:2.0
PRODID:icalendar-ruby
CALSCALE:GREGORIAN
BEGIN:VEVENT
DTSTAMP:20260808T210735Z
UID:c4221e8e-2e0a-4862-867a-8fe70b4b105f
DTSTART:20250210T100000Z
DTEND:20250212T150000Z
DESCRIPTION:Genome assembly is the process of piecing together fragments of
  DNA to reconstruct the original genome. The genome provides crucial infor
 mation for understanding genetic structure\, function and variation. In re
 cent years\, long-read sequencing technologies have revolutionized genome 
 assembly. These long reads can span repetitive sequences and structural va
 riations making genome assembly simpler but also reducing gaps and fragmen
 ts in the genome\, resolve repeats\, help with the detection of structural
  variation as well as improved haplotype phasing. During this course we wi
 ll look at data generated using PacBio and Oxford Nanopore\, discuss the p
 ros and cons of both sequencing technologies and the effect they might hav
 e on genome assembly. During the course we will look at different tools av
 ailable to generate assemblies\, focussing on de novo genome assembly. Pol
 ishing using short or long reads and the introduction of Hi-C sequencing c
 an increase completeness of the genomes. At the difference steps during th
 e assembly process we will look at the contiguity\, completeness and corre
 ctness of the generated genomes\, thereby evaluation the status of the gen
 ome. Once a genome has been assembled the next step is annotation. Genome 
 annotation involves identifying and mapping locations of genes and other f
 unctional elements within the sequenced genome. We will take a look at the
  differences between prokaryote and eukaryote genomes and the tools availa
 ble for annotation. We will talk about steps to improve annotation once th
 e automatic annotation has been made.
SUMMARY:Genome Assembly and Annotation
URL;VALUE=URI:https://genomics.ed.ac.uk/event/genome-assembly-and-annotatio
 n/
END:VEVENT
END:VCALENDAR