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DTSTAMP:20260627T223435Z
UID:849eadb7-69e2-4e10-b0b1-4290d65409f3
DTSTART:20240418T090000Z
DTEND:20240506T170000Z
DESCRIPTION:The plummeting costs for sequencing over the last decades\, all
 ow whole genome resources to be built in a single lab\, for a single proje
 ct. While accessible to most\, the process still demands informed decision
 -making and navigation through potential pitfalls.\n\nHigh-quality genome 
 assemblies are key for deciphering the biology of an organism\, paving the
  way for diverse downstream analyses:\n\n\n	genetic variations: Identify 
 mutations linked to disease\, adaptation\, or other phenotypes.\n	gene f
 unction: Delve into the roles and networks of genes within the organism.\
 n	evolutionary history: Chart the path of genetic divergence and understa
 nd relationships between species.\n	comparative insights: Analyze similar
 ities and differences across genomes to uncover broader biological princip
 les.\n\n\nGenome assembly has been revolutionized by long-read sequencing 
 technologies\, particularly by PacBio HiFi and Oxford Nanopore Technology.
  These technologies overcome the limitations of short-read methods\, in as
 sembling complex genomes with high levels of repetitive regions. As a resu
 lt\, they are currently the obvious choice for generating de novo referenc
 e genomes.\n\nWhile a number of assembly pipelines and algorithms exist\, 
 informed decision-making\, from defining your project goals and crafting o
 ptimal sequencing strategies to assessing the final assembly\, each step h
 olds critical implications for success.\n\nUltimately\, the reward is a re
 ference genome of your target organism that will lay the foundation on whi
 ch downstream experiments can be built.
LOCATION:Ghent - VIB/UGent FSVM II\, Technologiepark 75
SUMMARY:High-Quality Genome Assembly with Long-Read Technology
URL;VALUE=URI:https://training.vib.be/all-trainings/high-quality-genome-ass
 embly-long-read-technology
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