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DTSTAMP:20260619T081639Z
UID:0086aaed-32a4-4666-8900-7693d51fb533
DTSTART:20211206T090000Z
DTEND:20211209T170000Z
DESCRIPTION:Computer models are increasingly used by researchers as well as
  the pharmaceutical industry to investigate disease initiation\, progressi
 on and therapy. Modelling of biochemical pathways deregulated in disease c
 ondition offers mechanistic insights into the pathology\; helps to elucida
 te mechanisms behind drug action and predict dose required for treatment a
 nd thereby greatly facilitates fundamental research and drug discovery. Su
 ch modelling requires a background in both molecular biology and mathemati
 cs. \n\nThe four days virtual workshop will train researchers from life s
 cience and mathematics to communicate and work together to learn to build 
 and analyse computer models using user-friendly open-source software. The 
 workshop will be jointly organised by the [BioModels](https://www.ebi.ac.u
 k/biomodels/) team from EMBL-EBI along with the Centre for Integrative Bio
 logy and Systems Medicine (IBSE) and the Robert Bosch Centre for Data Scie
 nces and Artificial Intelligence ([RBC-DSAI](https://rbcdsai.iitm.ac.in/))
  from Indian Institute of Technology Madras (IITM). Various modelling appr
 oaches and tools will be introduced to the participants. They will explore
  a few of the disease-specific computer models from a recent publication\,
  freely available in [BioModels](https://www.ebi.ac.uk/biomodels/) reposit
 ory.\n\nOther EMBL-EBI resources including [Reactome](https://reactome.org
 /)\, [IntAct](https://www.ebi.ac.uk/intact/home)\, [OmicsDI](https://www.o
 micsdi.org/)\, [PRIDE](https://www.ebi.ac.uk/pride/)\, [ExpressionAtlas](h
 ttps://www.ebi.ac.uk/gxa/home) will be introduced to the participants. The
  BioModels team will lead the training on kinetic modelling of signalling 
 pathways\, curation and annotation of mathematical models as well as stand
 ards in modelling (SBML\, SED-ML\, etc). The IITM/IBSE team will partner i
 n the training on kinetic modelling approaches\, and also introduce other 
 paradigms such as constraint-based modelling (e.g. Flux Balance Analysis (
 FBA)) for the analysis of metabolic pathways.   \n\nAn essential agenda
  in the meeting will be group projects where participants from both experi
 mental and theoretical background would work together to curate mathematic
 al models and submit them to the BioModels repository. This workshop will 
 allow EMBL-EBI to partner with IITM to share expertise on kinetic modellin
 g and gain expertise on the curation of non-kinetic models (specifically\
 , constraint-based models\, using the newly developed [FBC curation packag
 es](https://www.ebi.ac.uk/biomodels/curation/fbc)) in BioModels repository
 . Furthermore\, this joint workshop would be used as an opportunity for lo
 ng term partnership with IITM to establish training for EMBL-EBI resources
  in India\, explore the possibility of joint data curation engagement and 
 scientific collaboration.
LOCATION:Bhupat and Jyoti Mehta School of Biosciences\, Bhupat and Jyoti Me
 hta School of Biosciences\, Indian Institute of Technology Madras
SUMMARY:IITM-EMBL-EBI Winter School 2021
URL;VALUE=URI:https://www.ebi.ac.uk/training/events/iitm-ebi-modelling-work
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