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VERSION:2.0
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CALSCALE:GREGORIAN
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DTSTAMP:20260407T180702Z
UID:d5348344-2193-4dd7-90a5-e575aba8c405
DTSTART:20261126T090000Z
DTEND:20261126T170000Z
DESCRIPTION:Genetic variation between individuals results in a range of hum
 an phenotypes. Variants that fall within coding regions of genes generally
  have direct effects on the proteins encoded by the genes with which they 
 overlap. This six-hour virtual workshop will provide participants with an 
 opportunity to gain hands-on experience of using EMBL-EBI tools and resour
 ces to assess the effects of genetic variants on the structure and functio
 n of proteins in a common workflow. \n\nDuring the course\, a single exam
 ple will be used throughout\, using different EMBL-EBI tools and resources
  at each stage of the analysis pipeline. The example will involve running 
 a Variant Call Format (VCF) file through the Ensembl Variant Effect Predic
 tor (VEP)\, then following links to UniProt\, PDBe\, and AlphaFoldDB for f
 urther variant information and interpretation. \n\n**Virtual course**\n\n
 This course will take place on Zoom. Trainers will be available to assist 
 during practical sessions\, answer questions\, and provide further explana
 tions during the Zoom.\n\nTo join the course you will need to create an [
 EMBL-EBI Training website account](https://www.ebi.ac.uk/training/user/reg
 ister).
SUMMARY:Interpreting the effects of genetic variants on protein structure a
 nd function
URL;VALUE=URI:https://www.ebi.ac.uk/training/events/interpreting-effects-ge
 netic-variants-protein-structure-and-function-2026
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