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DTSTAMP:20260708T150518Z
UID:50bd7ae9-8184-438f-a446-346c9624bc28
DTSTART:20211022T090000Z
DTEND:20211022T120000Z
DESCRIPTION:The recent years have seen the emergence of the microbiomes as 
 important axes of human health and disease. Microbial communities abound i
 n various regions of the human body\, notably the gut\, skin and the oral 
 cavity. Microbial communities are increasingly being used for industrial f
 ermentations and wastewater treatment. \n\nMany algorithms and tools have 
 been developed to study microbial communities\, particularly the metabolic
  interactions that drive and sustain these microbial communities. **In thi
 s tutorial\, we seek to provide a brief overview of the key modelling para
 digms that have been used to study microbiomes\, particularly focussing on
  two broad classes of methods: (a) constraint-based modelling\, that attem
 pts to model microbial metabolic networks in terms of the fluxes of variou
 s constituent reactions\, and (b) graph-based modelling\, which models mic
 robial interactions as part of a complex graph capturing the exchange of s
 everal metabolites between the constituent organisms\, and consequently\, 
 shed light on the nature of the interactions between the organisms.\n\nIn 
 this tutorial\, we will introduce the participants to the fundamental conc
 epts of metabolic modelling with a special emphasis on microbial communiti
 es. Following this\, we will delve deeper into different types of techniqu
 es to understand interactions in a microbial community. Lastly\, we will s
 howcase some representative tools and methods\, which will enable the part
 icipants to apply the theories to real-life examples and understand the na
 ture of interactions between different kinds of organisms in community set
 tings. \n**At the end of the tutorial\, the participants will have an unde
 rstanding of:** \n\n- Broad applications of metabolic modelling to model m
 icrobiome \n- Databases and resources for microbiome modelling \n- Key con
 straint-based methods that can be used to understand microbiome \n- Key gr
 aph-based methods that can aid in understanding metabolic exchanges \n- To
 ols for microbiome modelling such as COBRA toolbox (specific algorithms) o
 r MetQuest
LOCATION:online
SUMMARY:Metabolic modelling of microbial interactions in microbiomes
URL;VALUE=URI:https://www.iscb.org/iscbacademy-upcoming#tutorial01
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