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DTSTAMP:20260708T054608Z
UID:3d7e3e6e-3468-400b-a589-759dc751aaa7
DTSTART:20190311T090000Z
DTEND:20190405T170000Z
DESCRIPTION:This training will provide an overview of the analytical techni
 ques and data analysis tools that are applied to study the metabolome and 
 will provide insights on how to interpret metabolomics data.\n\nThe first 
 day of lectures (Monday 11 March 2019\, Leuven) will cover recent developm
 ents and breakthroughs in the application of metabolomics. We will start 
 the day with an overview of sampling preparation requirements for metabolo
 mics and data analysis pipelines available at VIB. Next session will focus
  on central metabolomics – including interpretation of labeling data\, l
 abeling data mapping and thermodynamics. Second session will be dedicated 
 to lipidomics of membrane lipids and fatty acids. Next\, secondary metabol
 omics approaches to identify and quantify secondary metabolites in both di
 scovery and targeted mode will be discussed. We will end the day with a ke
 ynote talk on metabolic fluxes.\n\nThere will also be two hands-on session
 s for which you need to register seperately:\n\n  \n\n\nHands-on sessio
 n with focus on secondary metabolism: Monday 1 April 2019\, iGent - Ghen
 t\n\nThis hands-on session will focus on the processing of raw data obtain
 ed via either Gas Chromatography- (GC) or Liquid Chromatography- (LC) mass
  spectrometry (MS). In addition\, based on the comparative analysis betwee
 n two sample sets (e.g. control vs treatment)\, the subsequent identificat
 ion of differential metabolites will be introduced. Afterwards\, the train
 ee should be able to perform independently a comparative analysis of raw m
 etabolome data and to pinpoint the well-known metabolites in the chromatog
 ram. This training is intended for people who have a basic knowledge of R
 . Participants who have never worked with R should first follow the cours
 e Basic statistics in R. We can provide a laptop for you\, or you may br
 ing your own laptop.\n\nTrainer: Kris Morreel\, VIB-UGent Center for Plan
 t Systems Biology​ ​\n\n \n\nHands-on session with focus on primary 
 metabolism: Friday 5 April 2019\, Park Inn Leuven\n\n During this sessio
 n we will perform the data-processing of GC-MS and LC-MS spectra obtained 
 from mammalian derived samples in a tracer-(13C)-metabolomics setup using 
 a software tool (EMFASYS) developed at the Metabolomics Expertise Center L
 euven. As such the focus will be on (1) the correct and consequent integra
 tion of isotopologue profiles and (2) the identification of central carbon
  metabolites. Different identification strategies will be demonstrated\, s
 uch as retention time – m/z and MS/MS based strategies. We will also tak
 e a first step towards the biochemical interpretation of some metabolite 
 13C- labeling patterns. Having some experience with command line interface
 s is recommended but not mandatory.\n\nTrainer: Dries Verdergem\, VIB Met
 abolomics Core Leuven​\n\n\n 
LOCATION:Leuven - Park Inn by Radisson\, Martelarenlaan 36
SUMMARY:Metabolomics Data interpretation
URL;VALUE=URI:https://training.vib.be/all-trainings/metabolomics-data-inter
 pretation
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