BEGIN:VCALENDAR VERSION:2.0 PRODID:icalendar-ruby CALSCALE:GREGORIAN BEGIN:VEVENT DTSTAMP:20260715T213045Z UID:aa81db33-dc44-48cd-bd5d-4757ab5e2ed7 DTSTART:20240905T090000Z DTEND:20240906T170000Z DESCRIPTION:The videos of the lectures can be found on the [SIB YouTube cha nnel](https://www.youtube.com/playlist?list=PLoCxWrRWjqB3syM9-pdUSIClc2QkV MmH1).\n\n# Overview \nThe detection of genetic variation is of major inte rest in various disciplines spanning from ecology and evolution research t o inherited disease discovery and precision oncology. Next generation sequ encing (NGS) methods are very powerful for the detection of genomic varian ts. Thanks to its throughput and cost-efficiency it enables the detection of a large number of variants in a large number of samples. In this two-da y course we will cover the steps from read alignment to variant calling an d annotation. We will mainly focus on the detection of germline mutations by following the GATK best practices. The training materials for this cour se are in its dedicated GitHub page.\n\n\n# Audience\nThis course is inten ded for life scientists who are already familiar with general concepts of NGS technologies and want to expand their knowledge and skills on variant analysis.\n\n# Learning objectives\nAt the end of the course participants should be able to:\n\n Understand important aspects of NGS and read alignm ent for variant analysis\n Perform a read alignment ready for variant anal ysis\n Perform variant calling according to GATK best practices\n Perform a variant annotation\n\n\n# Prerequisites\n***Knowledge / competencies:*** \nParticipants should have knowledge in NGS techniques\, quality control a nd alignment to a reference genome. Participants should have a basic under standing of working with command line tools on Unix-based systems. You can test your skills with Unix with the quiz here. If you do not feel comfort able with UNIX commands\, please take our Unix fundamentals e-learning mod ule.\n\n**Technical:**\nParticipants should have their own computers. \n\ n# Application\n\n\nRegistration fees are **200 CHF** for academics and ** 1000 CHF** for for-profit companies. \n\nWhile participants are registered on a first come\, first served basis\, exceptions may be made to ensure d iversity and equity\, which may increase the time before your registration is confirmed.\n\nApplications will close as soon as the places will be fi lled up\, until **15/08/2024**. Deadline for free-of-charge cancellation i s set to **22/08/2024**. Cancellation after this date will not be reimburs ed. Please note that participation to SIB courses is subject to our [gener al conditions](https://www.sib.swiss/training/terms-and-conditions).\n\nYo u will be informed by email of your registration confirmation. Upon recept ion of the confirmation email\, participants will be asked to confirm atte ndance by paying the fees within 5 days.\n\n# Location\nThis course will b e held online via Zoom.\n\nIt will start at 9:00 and end around 17:00 CEST .\n\nPrecise information will be provided to the participants in due time. \n\n# Schedule\n\nThe schedule and course materials are on the dedicated [ GitHub page](https://sib-swiss.github.io/NGS-variants-training/latest/cour se_schedule/). \n\n\n# Additional information\n\nCoordination: Diana Marek \, SIB training group\n\nWe will recommend 0.5 ECTS credits for this cours e (given a passed exam at the end of the session). \n\nYou are welcome to register to the SIB courses mailing list to be informed of all future cou rses and workshops\, as well as all important deadlines using the form [he re](https://lists.sib.swiss/postorius/lists/courses.lists.sib.swiss/).\n\n Please note that participation in SIB courses is subject to our [general c onditions](https://lists.sib.swiss/postorius/lists/courses.lists.sib.swiss /).\n\nSIB abides by the [ELIXIR Code of Conduct](https://elixir-europe.or g/events/code-of-conduct). Participants of SIB courses are also required t o abide by the same code.\n\nFor more information\, please contact [traini ng@sib.swiss](mailto://training@sib.swiss). SUMMARY:NGS - Genome Variant Analysis URL;VALUE=URI:https://www.sib.swiss/training/course/20240905_NGSGV END:VEVENT END:VCALENDAR