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DTSTAMP:20260615T174714Z
UID:658d05f4-44a1-45bb-90ad-545dc1dfe8cb
DTSTART:20181116T100000Z
DTEND:20181116T220000Z
DESCRIPTION:Workshop will concentrate on using the dinucleotide conformers 
 (NtC) as a tool\nenabling more reliable solution of crystal and cryo-EM st
 ructures of nucleic acids. The current\nversion of the dnatco.org web serv
 er as well as the development version introducing a\nuniversal (for both D
 NA and RNA) set of NtC classes will be demonstrated.\n\nWe will show proto
 type of the procedure(s) to fit our library of the dinucleotide\nconformer
 s to electron density\, as well as method of building NA models with the u
 ser\nspecified NtC sequence\, and morphing between two NA structures. All 
 that by using\nMacroMoleculeBuilder (MMB) by Samuel Flores. Sam will be pr
 esent to show these new\nfunctions.\n\nImportantly\, we also work with Pau
 l Emsley on new Coot features. We currently\nconcentrate on initial model 
 building by fitting into experimental electron density and validation\nusi
 ng the NtC. Paul is unavailable for the meeting but we shall be able to pr
 esent and discuss\nall new and planned Coot features concentrating on the 
 synergy between different tools.\nYour presence would be extremely importa
 nt to be able to look at the initial model\nbuilding and validation from u
 ser's perspective and suggest improvements of an early phase\nof building 
 a truly useful tool. It will be great if you bring your own problem to tes
 t the\nemerging system.\n\nWe will try to cover two nights (Nov 15-16 and 
 16-17) in a hotel including breakfast\n( www.hotel-ilf.cz ). There is also
  no registration fee for the workshop thanks to the support\nprovided by t
 he ELIXIR-CZ.\n\nFor more details contact Jiří Černý ( jiri.cerny@ibt.
 cas.cz )\, ideally till November 7.\n
LOCATION:V Sadech 1/1\, 1\, V Sadech
SUMMARY:Nucleic acids model building workshop
URL;VALUE=URI:https://www.biocev.eu/
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