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DTSTAMP:20260616T093251Z
UID:5d16006c-95d5-4fc9-bb12-b970efbc0c6a
DTSTART:20211025T083000Z
DTEND:20211029T173000Z
DESCRIPTION:Precision Oncology (PO) is already revolutionizing healthcare a
 nd will play a dominant role in the future of cancer therapy. PO integrate
 s tumor multi-omic profiles and data that reflect the course of the diseas
 e\, lifestyle and environment to guide clinical decisions during cancer pa
 tient journey such as prevention\, diagnosis and treatment. Bioinformatics
  analyses are essential to identify patients who will benefit from treatme
 nt based on their molecular profile\, and to tailor chemotherapeutic regim
 ens accordingly. The aim of the course is to present a complete computatio
 nal pipeline for the analysis and interpretation of Next-Generation Sequen
 cing (NGS) data such as exome sequencing or targeted panels that are commo
 nly used in the clinic. We will address the implementation of large-scale 
 genomic sequencing in clinical practice and the recently developed computa
 tional strategies for the analysis of NGS data with a particular emphasis 
 on the interpretation of the results\, selection of biomarkers of drug res
 ponse and afford opportunities to match therapies with the characteristics
  of the individual patient's tumor. Exercises and case studies focused on 
 cancer will be used to illustrate the principles of how genetics influence
  led to refining diagnoses and personalized treatment of cancer disease. A
 lthough focused on cancer\, some of the principles and steps could be extr
 apolated to other complex diseases.\n
LOCATION:Instituto Gulbenkian de Ciência
SUMMARY:PO21 Precision Oncology
URL;VALUE=URI:http://gtpb.igc.gulbenkian.pt/bicourses/2021/PO21/
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