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DTSTAMP:20260615T034607Z
UID:30a44703-1a40-410f-a17f-f85267633026
DTSTART:20220509T083000Z
DTEND:20220513T170000Z
DESCRIPTION:Precision Oncology (PO) is already revolutionizing healthcare a
 nd will play a dominant role in the future of cancer therapy. PO integrate
 s tumor multi-omic profiles and data that reflect the course of the diseas
 e\, lifestyle and environment to guide clinical decisions during cancer pa
 tient journey such as prevention\, diagnosis and treatment. Bioinformatics
  analyses are essential to identify patients who will benefit from treatme
 nt based on their molecular profile\, and to tailor chemotherapeutic regim
 ens accordingly. The aim of the course is to present a complete computatio
 nal pipeline for the analysis and interpretation of Next-Generation Sequen
 cing (NGS) data such as exome sequencing or targeted panels that are commo
 nly used in the clinic.We will address the implementation of large-scale g
 enomic sequencing in clinical practice and the recently developed computat
 ional strategies for the analysis of NGS data with a particular emphasis o
 n the interpretation of the results\, selection of biomarkers of drug resp
 onse and afford opportunities to match therapies with the characteristics 
 of the individual patient's tumor. Exercises and case studies focused on c
 ancer will be used to illustrate the principles of how genetics influence 
 led to refining diagnoses and personalized treatment of cancer disease. Al
 though focused on cancer\, some of the principles and steps could be extra
 polated to other complex diseases. 
LOCATION:Instituto Gulbenkian de Ciência
SUMMARY:PO22 Precision Oncology
URL;VALUE=URI:http://gtpb.igc.gulbenkian.pt/bicourses/2022/PO22
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