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DTSTAMP:20260618T080514Z
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DESCRIPTION:This three-day course will introduce concepts vital to biocurat
 ion\, including metadata and ontologies\, the role of identifiers\, and ex
 tracting data from literature. \n\nDuring the course\, there will be a fo
 cus on practical skills required by biocurators\, including programming fo
 r handling large biological datasets\, and querying databases. Participant
 s will have the opportunity to use these skills in a real-life practical b
 iocuration exercise during the group projects. \n\nThere will also be an 
 opportunity to network with biocurators and learn more about their roles a
 nd data resources.\n\n### Group projects\n\nA major element of this course
  is a group project\, where participants will be placed in small groups to
  work together on a challenge set by trainers from EMBL-EBI and external i
 nstitutes. This allows people to explore the role of biocurators and provi
 de participants with hands-on experience in biocuration. The group work wi
 ll culminate in a presentation session involving all participants on the f
 inal day of the course\, giving an opportunity for wider discussion in the
  whole course group.\n\nGroups are mentored and supported by the trainers 
 who set the initial challenge\, but the groups will be responsible for dri
 ving their projects forward\, with all members expected to take an active 
 role. Groups are pre-organised before the course.\n\nBasic outlines of the
  projects on offer this year are given below. In your registration you mus
 t indicate your first and second choice of project. Not all projects may b
 e offered\, and final decisions on which projects will be run during the c
 ourse will be made based on the number of applicants per project.\n\n**Gro
 up project: Curating a protein complex**\n\nIn this project\, a new protei
 n complex has been published and it is your role to find out as much infor
 mation as possible about the complex. Using literature and bioinformatics 
 resources\, you will provide an overview of the protein complex including 
 a full list of the complex members\, a description of the role of each pro
 tein and an overview of the role of the complex. You will use resources su
 ch as UniProt\, PDB and EuropePMC.\n\nProject mentor: Michele Magrane\n\n*
 *Group project: Exploring data and metadata from a genome-wide association
  study**\n\nThe GWAS Catalog is a richly-annotated database of human genom
 e-wide association studies\, which analyse associations between genetic va
 riants and a disease or other trait of interest in a sample of individuals
  from a particular population. In this mini project you will examine a GWA
 S publication in detail\, to extract information about the traits and samp
 les under investigation and decide how to represent these metadata using s
 tandardised vocabularies and ontologies. You will also use simple command 
 line tools to look at a GWAS dataset and explore the role of standard form
 ats and quality control in biocuration.\n\nProject mentor: Elliot Sollis\n
 \n**Group project****: Using alignments to improve Rfam families: a case o
 f curating non-coding RNA families**\n\nRfam is the database of non-coding
  RNAs (ncRNAs) families. These families are built out of a sequence alignm
 ent\, metadata describing the family and an infernal model. Each family is
  built by curating alignments from publications or user submitted alignmen
 ts. In this project we will demonstrate the process of updating an existin
 g family with an improved alignment. We will examine the reports generated
  during curation. In this process\, we will examine the phylogenetic distr
 ibution\, sequence alignment and model results to determine how the family
  should be updated to reflect the improved alignment. Additionally\, we wi
 ll show how to connect this information to resources like Wikipedia.\n\nPr
 oject mentor: Nancy Ontiveros\n\n 
LOCATION:European Bioinformatics Institute\, Hinxton
SUMMARY:Practical biocuration
URL;VALUE=URI:https://www.ebi.ac.uk/training/events/practical-biocuration
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