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DTSTAMP:20260715T222347Z
UID:cae2723a-1460-488f-9bb1-ff6707f02c77
DTSTART:20151207T090000Z
DTEND:20151208T000000Z
DESCRIPTION: Hand on training workshop (7 Dec 2015) &amp\; Hot Topic Meetin
 g (8 Dec 2015)    The Biochemical Society at Charles Darwin House\, London
   Organised by Christine Orengo (UCL) and Mike Sternberg (Imperial)   Prot
 ein modelling has become increasingly important with the explosion in the 
 number of determined genomes and the challenges of interpreting clinical s
 tudies of human variation such as being obtained from the Genomics England
  initiative.  The hot topic meeting will review the status of a wide range
  of modelling tools highlighting the underpinning principles\, how to get 
 the most out of the features available and the directions for development.
  We will describe resources for analysis of multiple sequence alignments (
 JALVIEW)\, classification and annotation of protein families (CATH\, SCOP 
 and SUPERFAMILY)\, protein structure prediction (FUGUE\, SWISSMODEL\, PHYR
 E2 and the PSIPRED workbench) and an integrated resource of protein annota
 tion (GENOME3D). Additionally\, several of the speakers have developed enh
 anced methods to predict whether a missense mutation is expected to be dis
 ease associated and these tools will be reported (FATHMM\, Duet and SUSPEC
 T). These resources will then be placed in the wider context of the applic
 ations and developments of protein modelling.  Speakers include: Geoff Bar
 ton\, Franca Fraternali\, Julian Gough\, Tim Hubbard\, David Jones\, Lawre
 nce Kelley\, Tony Andreeva\, Bernardo Ochoa\, Ian Sillitoe\, Torsten Schwe
 de and Janet Thornton.  On the first day we will run a smaller introductor
 y hands-on tutorial and workshop (7 December 2015) for biologists and clin
 icians less familiar with the field which will focus on sequence alignment
  (Geoff Barton\, Dundee)\, structural families (Christine Orengo\, UCL) an
 d protein structure and variant prediction  (Mike Sternberg and Lawrence 
 Kelley\, Imperial).  You can register for either or both days.  
SUMMARY:Protein New Developments in Protein Structure Modelling for Biologi
 cal and Clinical Research
URL;VALUE=URI:http://bivi.co/event/protein-new-developments-protein-structu
 re-modelling-biological-and-clinical-research
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