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DESCRIPTION:# Overview\nUsing high-throughput technologies\, you can identi
 fy long lists of candidate genes that differ between two experimental cond
 itions. In order to interpret these gene lists and to discover fundamental
  properties like gene function and disease relevance\, you need to use the
  annotation linked to a given gene or protein sequence.\n\nThe goals of th
 is course are to give some basic theoretical and practical knowledge on pr
 otein sequence databases with a focus on [UniProtKB](https://www.uniprot.o
 rg/)\, on the different manual and automated annotation pipelines (such as
  [HAMAP](https://hamap.expasy.org/)) and\, in particular\, on the optimum 
 use of UniProtKB. UniProtKB and HAMAP are SIB resources\; they are listed 
 in [Expasy](https://www.expasy.org/)\, the Swiss Bioinformatics Portal. Du
 ring the lecture and exercise  sessions\, we will cover questions such as:
 \n* Where do the protein sequences come from?\n* What are the differences 
 between the major protein sequence databases?\n* What are the manual and a
 utomated gene / protein annotation pipelines?\n* What are the Gene Ontolog
 y (GO) annotation pipelines?\n* How to assess protein sequence accuracy an
 d annotation quality?\n* How to extract biological knowledge from a Blast 
 result or gene list?\n\n# Audience\nThis course targets biologists and bio
 informaticians who seek to analyze protein data. It will also be useful to
  programmers and data scientists\, be they from academia or industry\, who
  programmatically access protein sequence databases and need to understand
  the data.\n\n# Learning outcomes\nAt the end of the course\, the particip
 ants are expected to:\n* list the differences between the major protein se
 quence databases\n* describe the major protein sequence and GO annotation 
 pipelines\n* assess the accuracy of a protein sequence and the quality of 
 annotation\n* use the query interfaces on the UniProtKB website to make me
 aningful and productive requests \n\n# Prerequisites\n##### Knowledge / co
 mpetencies\nThis course is designed for beginners. There are no requiremen
 ts.\n##### Technical\nThis course will be streamed\, you are thus required
  to have your own computer with an Internet connection.\n\n# Application\n
 The registration fees for academics are **100 CHF** and **500 CHF** for fo
 r-profit companies. While participants are registered on a first come\, fi
 rst served basis\, exceptions may be made to ensure diversity and equity\,
  which may increase the time before your registration is confirmed. \n\nYo
 u will be informed by email of your registration confirmation. Upon recept
 ion of the confirmation email\, participants will be asked to confirm atte
 ndance by paying the fees within 5 days.\n\nDeadline for free-of-charge ca
 ncellation is set to **14/04/2023**. Cancellation after this date will not
  be reimbursed. Please note that participation in SIB courses is subject t
 o our [general conditions](https://www.sib.swiss/training/terms-and-condit
 ions).\n\n# Venue and Time\nThis course will take place at the University 
 of Lausanne.\n\nThe course will start at 9:00 CET and end around 17:00 CET
 . \n\nPrecise location will be communicated to the participants in due tim
 e.\n\n\n#  Additional information\nCoordination: Grégoire Rossier\, SIB t
 raining group.\n\nWe will recommend 0.25 ECTS credits for this course (giv
 en a passed exam at the end of the course).\n\nYou are welcome to register
  to the SIB courses mailing list to be informed of all future courses and 
 workshops\, as well as all important deadlines using the form [here](https
 ://lists.sib.swiss/mailman/listinfo/courses).\n\nPlease note that particip
 ation in SIB courses is subject to our [general conditions](https://www.si
 b.swiss/training/terms-and-conditions).\n\nSIB abides by the [ELIXIR Code 
 of Conduct](https://elixir-europe.org/events/code-of-conduct). Participant
 s of SIB courses are also required to abide by the same code.\n\nFor more 
 information\, please contact [training@sib.swiss](mailto://training@sib.sw
 iss).
SUMMARY:Protein Sequence Databases and Sequence Annotation at UniProtKB
URL;VALUE=URI:https://www.sib.swiss/training/course/20230428_PRODB
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