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DTSTAMP:20260709T194902Z
UID:7095de75-cb88-4852-b639-364acb5b00ec
DTSTART:20260319T093000Z
DTEND:20260320T173000Z
DESCRIPTION:Determining the 3 dimensional (3D) structure of a protein from 
 its amino sequence is vital for understanding its core biological function
 s. This can be done using experimental approaches\, which are the standard
  for validating high-resolution and accurate structures. However\, these m
 ethods can be costly\, time-consuming and technically difficult to achieve
  for certain proteins. To complement these approaches\, computational meth
 ods can be used\, which increase the speed of prediction\, can be scaled t
 o higher throughput and are much cheaper to run. \n\nThis course covers ho
 w to computationally predict the 3D structure of proteins from their amino
  acid sequences. We will focus on  AlphaFold\, a software that has revolut
 ionised this process due to its outstanding (near-experimental) prediction
  accuracy. Other key aspects will be covered such as retrieving structural
  information from public databases\, evaluating the quality of the predict
 ed models\, model visualisation with ChimeraX\, multimer predictions\, pre
 diction of ligand binding sites and docking. After this course you should 
 be able to produce 3D predictions of your proteins\, while critically eval
 uating the output of the methods covered in the course. \n\n\nIf you do no
 t have a University of Cambridge [Raven account](https://legacy.raven.cam.
 ac.uk/auth/account/) please book or register your interest [here](http://b
 ioinfotraining.bio.cam.ac.uk/booking-form/?event-id=5855264&amp\;course-ti
 tle=Protein%20Structure%20Modelling%20in-person).\nIf for any reason the a
 bove links do not work\, please email [Research Informatics Training Team]
 (https://training.cam.ac.uk/bioinformatics/info/contact) with details of y
 our course enquiry.\n\nAdditional information\n\n* ♿ The training room i
 s located on the first floor and there is currently no wheelchair or level
  access.\n* Our courses are only free for registered University of Cambrid
 ge students. All other participants will be charged according to our  [cha
 rging policy](http://www.training.cam.ac.uk/bioinformatics/info/charging).
 \n* Attendance will be taken on all courses and a charge is applied for no
 n-attendance. After you have booked a place\, if you are unable to attend 
 any of the live sessions\, please email the [Research Informatics Training
  Team](https://training.cam.ac.uk/bioinformatics/info/contact).\n* Further
  details regarding eligibility criteria are available [here](http://www.tr
 aining.cam.ac.uk/bioinformatics/info/eligibility).\n* Guidance on visiting
  Cambridge and finding accommodation is available [here](https://bioinfotr
 aining.bio.cam.ac.uk/about).
LOCATION:Craik-Marshall Building
SUMMARY:Protein structure modelling (IN-PERSON)
URL;VALUE=URI:http://training.csx.cam.ac.uk/bioinformatics/event/5855264
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