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BEGIN:VEVENT
DTSTAMP:20260618T124452Z
UID:4cec4fad-8ad2-4e0b-b3c4-3b30d19c4e3c
DTSTART:20250303T093000Z
DTEND:20250306T130000Z
DESCRIPTION:Determining the 3 dimensional (3D) structure of a protein from 
 its amino sequence is vital for understanding its core biological function
 s. This can be done using experimental approaches\, which are the standard
  for validating high-resolution and accurate structures. However\, these m
 ethods can be costly\, time-consuming and technically difficult to achieve
  for certain proteins. To complement these approaches\, computational meth
 ods can be used\, which increase the speed of prediction\, can be scaled t
 o higher throughput and are much cheaper to run. \n\nThis course covers ho
 w to computationally predict the 3D structure of proteins from their amino
  acid sequences. We will focus on  AlphaFold\, a software that has revolut
 ionised this process due to its outstanding (near-experimental) prediction
  accuracy. Other key aspects will be covered such as retrieving structural
  information from public databases\, evaluating the quality of the predict
 ed models\, model visualisation with ChimeraX\, multimer predictions\, pre
 diction of ligand binding sites and docking. After this course you should 
 be able to produce 3D predictions of your proteins\, while critically eval
 uating the output of the methods covered in the course. \n\n\nIf you do no
 t have a University of Cambridge [Raven account](https://legacy.raven.cam.
 ac.uk/auth/account/) please book or register your interest [here](http://b
 ioinfotraining.bio.cam.ac.uk/booking-form/?event-id=5168809&amp\;course-ti
 tle=Protein%20Structure%20Modelling%20in-person).\n\nAdditional informatio
 n\n\n* ♿ The training room is located on the first floor and there is cu
 rrently no wheelchair or level access.\n* Our courses are only free for re
 gistered University of Cambridge students. All other participants will be 
 charged according to our  [charging policy](http://www.training.cam.ac.uk/
 bioinformatics/info/charging).\n* Attendance will be taken on all courses 
 and a charge is applied for non-attendance. After you have booked a place\
 , if you are unable to attend any of the live sessions\, please email the 
 [Research Informatics Training Team](https://training.csx.cam.ac.uk/bioinf
 ormatics/info/contact).\n* Further details regarding eligibility criteria 
 are available [here](http://www.training.cam.ac.uk/bioinformatics/info/eli
 gibility).\n* Guidance on visiting Cambridge and finding accommodation is 
 available [here](https://bioinfotraining.bio.cam.ac.uk/about).
LOCATION:Craik-Marshall Building
SUMMARY:Protein structure modelling (IN-PERSON)
URL;VALUE=URI:http://training.csx.cam.ac.uk/bioinformatics/event/5168809
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