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DTSTART:20210602T020000Z
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DESCRIPTION:Mass spectrometry-based phosphoproteomics is one of the most po
 werful tools available for investigating the detailed molecular events tha
 t occur in response to cellular stimuli. Experiments can routinely detect 
 and quantify thousands of phosphorylated peptides\, and interpreting this 
 data\, and extracting biological meaning\, remains challenging. \n\nThis w
 ebinar will provide an overview of the phosphoproteomics data analysis web
 site\, Phosphomatics\, that incorporates a suite of tools and resources fo
 r statistical and functional analysis that aim to simplify the process of 
 extracting meaningful insights from experimental results.\n\nPhosphomatics
  can natively import search and quantitation results from major search eng
 ines including MaxQuant and Proteome Discoverer and employs intuitive ‘w
 izards’ to guide user through data preprocessing routines such as filter
 ing\, normalization and transformation. A graphical platform of interactiv
 e univariate and multivariate analysis features is provided that allow sub
 groups of the uploaded data containing phosphosites of statistical interes
 t to be created and interrogated through further functional analysis. A ra
 nge of databases have been integrated that\, for example\, provide ligand 
 and inhibitor information for key proteins or highlight key modification s
 ites known to be involved in functional state regulation. At each step\, p
 ublished literature is natively incorporated along with a ‘bibliography 
 builder’ that allows references of interest to be assembled and exported
  in various formats. Taken together\, these expanded features aim to provi
 de a ‘one-stop-shop’ for phosphoproteomics data analysis.\n\nPresenter
 : Dr Michael Leeming\, Research Fellow\, Mass Spectrometry and Proteomics 
 Facility\, University of Melbourne\n\nDate/time: 2 June 2021 - 12:00-13:00
  AEST / 11:30 - 12:30 ACST / 10:00-11:00 AWST\n\n[**Register here**](https
 ://unimelb.zoom.us/webinar/register/WN_kqno1eeTQK6pYZ0LYuqV2Q)
SUMMARY:WEBINAR: Making sense of phosphoproteomics data with Phosphomatics
URL;VALUE=URI:https://www.biocommons.org.au/events/phosphomatics
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