e-learning
Formation of the Super-Structures on the Inactive X
Abstract
Within a cell nucleus, the DNA is tightly-packed and the chromatin is spatially distributed with different levels and scales of organizations.
About This Material
This is a Hands-on Tutorial from the GTN which is usable either for individual self-study, or as a teaching material in a classroom.
Questions this will address
- Histone modification?
- How is a raw set of ChIP-seq data processed and analyzed?
- Where are the enriched regions for H3K27me3, H3K4me3 and CTCF on the chrX?
Learning Objectives
- Inspect the read quality
- Trim low quality bases
- Map reads on a reference genome
- Assess the quality of a ChIP-seq experiment
- Extract coverage files
- Call enriched regions or peaks
Licence: Creative Commons Attribution 4.0 International
Keywords: ChIP-seq, Epigenetics
Competency level: • Beginner
Target audience: Students
Resource type: e-learning
Version: 16
Status: Active
Prerequisites:
- Introduction to Galaxy Analyses
- Mapping
- Quality Control
Learning objectives:
- Inspect the read quality
- Trim low quality bases
- Map reads on a reference genome
- Assess the quality of a ChIP-seq experiment
- Extract coverage files
- Call enriched regions or peaks
Date modified: 2026-04-13
Date published: 2018-09-17
Authors: 
Anika Erxleben, Fidel Ramirez, Friederike Dündar, Leily Rabbani, Vivek Bhardwaj, Bérénice Batut, Pavankumar Videm
Contributors: Gildas Le Corguillé, Joachim Wolff, Leily Rabbani, Anup Kumar, Armin Dadras, Björn Grüning, Bérénice Batut, Cristóbal Gallardo, Florian Heyl, Helena Rasche, Martin Čech, Pavankumar Videm, Saskia Hiltemann, Tristan Reynolds
Scientific topics: Epigenomics
Activity log
