Duration

The workshop will take place 3 - 8 February 2019 at Station Biologique de Roscoff, France

Objectives

This workshop focuses on the large-scale study of heterogeneity across individual cells from a genomic, transcriptomic and epigenomic point of view. New technological developments enable the characterization of molecular information at a single cell resolution for large numbers of cells. The high dimensional omics data that these technologies produce come with novel methodological challenges for the analysis. In this regard, specific bioinformatics and statistical methods have been developed in order to extract robust information.

The workshop aims to provide such methods for engineers and researchers directly involved in functional genomics project making use of single-cell. A wide range of single cell topics will be covered in lectures, demonstrations and practical classes. Among others, the areas and issues to be addressed will include the choice of the most appropriate single-cell sequencing technology, the experimental design and the bioinformatics and statistical methods and pipelines.

Audience

This course is directed towards engineers and researchers who regularly need to undertake single-cell data analysis as well as PhD Student and Post Doc in computational biology or bioinformatics that are interested in the development of methods and pipelines for highly dimensional single-cell data analysis.

Working environment

Unix command will be used for bioinformatic analysis, and R programming language for statistical analysis.

Requirements

Understanding of bioinformatics tools and pipelines for next generation sequencing data (RNA-seq or Hi-C or ATAC-seq bulk). Participants must have prior experience on NGS data analysis with R and basic Unix command line skills.

Registration

Deadline : 15th novembre 2018 (participants selection: end of November 2018). As the number of participants is limited (30 participants), the steering committee will retain candidates on the basis of the information inquired on the registration form.

Frais d’inscription pour les personnels académiques

Registration fees. A) Academy/University: 600€HT=720€TTC ; B) Private sector: 1.750€HT=2.100€TTC. The registration fee includes accommodation and meals.

Scientific coordination:​ ​ Marc Deloger (Institut Curie, INSERM U900, Mines ParisTech), Marie-Agnès Dillies, C3BI (USR 3756 IP CNRS), Agnès Paquet, UCAGenomiX (IPMC CNRS), Antonio Rausell (Institut Imagine, INSERM UMR-1163), Nicolas Servant (Institut Curie, INSERM U900, Mines ParisTech), Morgane Thomas-Chollier, IBENS (CNRS UMR8197, ENS, INSERM U1024).

Technical coordination :​ ​ Erwan Corre (ABIMS FR2424 CNRS-UPMC, Station Biologique de Roscoff)

Administrative management​ :​ ​ C3BI (Institut Pasteur)